Annals of Colorectal Research Annals of Colorectal Research Ann Colorectal Res http://www.colorectalresearch.com 2322-5262 2322-5289 10.5812/acr. en jalali 2017 6 26 gregorian 2017 6 26 2 2
en 10.17795/acr-19705 Pilonidal Disease: Review of Recent Literature Pilonidal Disease: Review of Recent Literature review-article review-article Context

Sacrococcygeal pilonidal disease is a common cause of patient’s referral to colorectal surgery services. Recently, numerous reports published about management of patients with pilonidal disease.

Evidence Acquisition

In this review, we gathered all the recent ten years evidences indexed in the PubMed database.

Results

Surgical management has been changed from invasive excision and secondary healing to minimal invasive and non-operative, primary closure methods and flap based techniques. Developing laser epilation had promising effects on reducing recurrence rate. Most of surgical techniques efficacy are shown with well-controlled studies.

Conclusions

Although recent evidences seems to describe current techniques efficacy but the absence of standardized pilonidal staging system made comparison of studies difficult and newer studies should be done regarding this issue.

Context

Sacrococcygeal pilonidal disease is a common cause of patient’s referral to colorectal surgery services. Recently, numerous reports published about management of patients with pilonidal disease.

Evidence Acquisition

In this review, we gathered all the recent ten years evidences indexed in the PubMed database.

Results

Surgical management has been changed from invasive excision and secondary healing to minimal invasive and non-operative, primary closure methods and flap based techniques. Developing laser epilation had promising effects on reducing recurrence rate. Most of surgical techniques efficacy are shown with well-controlled studies.

Conclusions

Although recent evidences seems to describe current techniques efficacy but the absence of standardized pilonidal staging system made comparison of studies difficult and newer studies should be done regarding this issue.

Pilonidal Sinus;Surgery;Review Pilonidal Sinus;Surgery;Review http://www.colorectalresearch.com/index.php?page=article&article_id=19705 Seyed Vahid Hosseini Seyed Vahid Hosseini Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Mohammad Rezazadehkermani Mohammad Rezazadehkermani Department of General Surgery, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran; Department of General Surgery, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran. Tel/Fax: +98-7112330724 Department of General Surgery, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran; Department of General Surgery, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran. Tel/Fax: +98-7112330724 Reza Roshanravan Reza Roshanravan Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Khairallah Muzhir Gabash Khairallah Muzhir Gabash Department of Surgery, Al-Karama Teaching Hospital, College of Medicine, Wasit University, Kut, Iraq Department of Surgery, Al-Karama Teaching Hospital, College of Medicine, Wasit University, Kut, Iraq Mahmoud Aghaie-Afshar Mahmoud Aghaie-Afshar Department of General Surgery, School of Medicine, Kerman University of Medical Sciences, Kerman, IR Iran Department of General Surgery, School of Medicine, Kerman University of Medical Sciences, Kerman, IR Iran
en 10.17795/acr-19917 BRAF Gene Mutation Analysis in Colorectal Cancer in South of Iran <italic>BRAF</italic> Gene Mutation Analysis in Colorectal Cancer in South of Iran research-article research-article Background

Colorectal carcinoma is the third most commonly diagnosed cancer worldwide and many studies have focused on its molecular basis. BRAF V600E is the single most important mutation of this gene in cancers. It shows variable, but usually low, frequency in colorectal cancer, but is associated with distinct histologic, prognostic and molecular features. It is highly associated with MSI (microsatellite instability), CIMP-H (CpG island methylator phenotype), serrated pathway, poor prognosis and resistance to anti-EGFR (epidermal growth factor) drugs and interestingly absent in Lynch syndrome.

Objectives

In this study, we analyzed BRAF V600E mutation in colorectal cancer in Iranian patients.

Patients and Methods

One hundred patients with colorectal cancer, operated in hospitals affiliated to Shiraz University of medical Sciences (Faghihi and Namazi Hospital) were selected. The cases were chosen from the pathology files of the above mentioned hospitals, during 2011-2013. Genomic DNA were extracted from the paraffin blocks, by the DNP TM kit, amplified using conventional PCR and DNA sequenced using the automated sequencer (Sanger method).

Results

Patients were 21-87 years old (mean = 59.8), 45% female and 55% male. Thirty percent of the cases had right-sided and 70% left-sided cancer, of which 83% were well and 17% moderately differentiated. No BRAF V600E mutation was detected in these 100 cases.

Conclusions

The BRAF mutation is not common in colorectal cancer patients in the South of Iran. Our results are very similar to very few previous studies conducted in Iran, although we suggest further studies with larger numbers of patients to confirm these results.

Background

Colorectal carcinoma is the third most commonly diagnosed cancer worldwide and many studies have focused on its molecular basis. BRAF V600E is the single most important mutation of this gene in cancers. It shows variable, but usually low, frequency in colorectal cancer, but is associated with distinct histologic, prognostic and molecular features. It is highly associated with MSI (microsatellite instability), CIMP-H (CpG island methylator phenotype), serrated pathway, poor prognosis and resistance to anti-EGFR (epidermal growth factor) drugs and interestingly absent in Lynch syndrome.

Objectives

In this study, we analyzed BRAF V600E mutation in colorectal cancer in Iranian patients.

Patients and Methods

One hundred patients with colorectal cancer, operated in hospitals affiliated to Shiraz University of medical Sciences (Faghihi and Namazi Hospital) were selected. The cases were chosen from the pathology files of the above mentioned hospitals, during 2011-2013. Genomic DNA were extracted from the paraffin blocks, by the DNP TM kit, amplified using conventional PCR and DNA sequenced using the automated sequencer (Sanger method).

Results

Patients were 21-87 years old (mean = 59.8), 45% female and 55% male. Thirty percent of the cases had right-sided and 70% left-sided cancer, of which 83% were well and 17% moderately differentiated. No BRAF V600E mutation was detected in these 100 cases.

Conclusions

The BRAF mutation is not common in colorectal cancer patients in the South of Iran. Our results are very similar to very few previous studies conducted in Iran, although we suggest further studies with larger numbers of patients to confirm these results.

Colorectal Cancer;Gene;Iran Colorectal Cancer;Gene;Iran http://www.colorectalresearch.com/index.php?page=article&article_id=19917 Farshid Javadi Farshid Javadi Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran Bita Geramizadeh Bita Geramizadeh Transplant Research Center, Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran; Transplant Research Center, Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran. Tel/Fax: +98-7116474331 Transplant Research Center, Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran; Transplant Research Center, Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran. Tel/Fax: +98-7116474331 Mitra Mirzai Mitra Mirzai Department of Pathology, Molecular Laboratory, School of Medicine, Namazi Teaching Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran Department of Pathology, Molecular Laboratory, School of Medicine, Namazi Teaching Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran
en 10.17795/acr-20062 Ultrasonography Accuracy for Perianal Fistula Anatomy Ultrasonography Accuracy for Perianal Fistula Anatomy research-article research-article Background

Endorectal ultrasonography is a diagnostic modality for evaluation of perianal pathologies and suitable surgical planning, especially in perianal fistula, due to its close relation to the anal sphincter complex. Detection of anatomical location of fistula tract and abscess is critical to select the best procedure.

Objectives

This study tries to demonstrate the accuracy of endorectal ultrasonography in mixed group of patients in diagnosing perianal fistula during two years, retrospectively.

Patients and Methods

After Ethics Committee approval, all endorectal ultrasonography reports of all patients with perianal fistula referred to Shiraz Endorectal Ultrasonography Clinic of Shiraz colorectal research center between 2010 and 2012 were gathered. All endorectal ultrasonographies in this center was perform by a colorectal surgeon with BK Medical Class I type B Ultrasonography scanner with 12 MHz probe.

Results

Finally, 183 cases of perianal fistula were enrolled in the study. Operation notes were evaluated and the type of fistula was compared with ultrasound findings. This study showed that endorectal ultrasonography has adequate accuracy with 97.92% sensitivity and acceptable 89.53% specificity in diagnosis of perianal fistula. Compared with other reports, it seems that endorectal ultrasonography is an acceptable diagnostic tool for detecting perianal fistula compared with other diagnostic modalities.

Conclusions

Endoanal sonography would be one of the high sensitive modalities for evaluation of perianal fistula. Detection of anatomy of fistula helps surgeon to choose best method for surgery.

Background

Endorectal ultrasonography is a diagnostic modality for evaluation of perianal pathologies and suitable surgical planning, especially in perianal fistula, due to its close relation to the anal sphincter complex. Detection of anatomical location of fistula tract and abscess is critical to select the best procedure.

Objectives

This study tries to demonstrate the accuracy of endorectal ultrasonography in mixed group of patients in diagnosing perianal fistula during two years, retrospectively.

Patients and Methods

After Ethics Committee approval, all endorectal ultrasonography reports of all patients with perianal fistula referred to Shiraz Endorectal Ultrasonography Clinic of Shiraz colorectal research center between 2010 and 2012 were gathered. All endorectal ultrasonographies in this center was perform by a colorectal surgeon with BK Medical Class I type B Ultrasonography scanner with 12 MHz probe.

Results

Finally, 183 cases of perianal fistula were enrolled in the study. Operation notes were evaluated and the type of fistula was compared with ultrasound findings. This study showed that endorectal ultrasonography has adequate accuracy with 97.92% sensitivity and acceptable 89.53% specificity in diagnosis of perianal fistula. Compared with other reports, it seems that endorectal ultrasonography is an acceptable diagnostic tool for detecting perianal fistula compared with other diagnostic modalities.

Conclusions

Endoanal sonography would be one of the high sensitive modalities for evaluation of perianal fistula. Detection of anatomy of fistula helps surgeon to choose best method for surgery.

Ultrasonography;Fistula;Sensitivity;Specificity Ultrasonography;Fistula;Sensitivity;Specificity http://www.colorectalresearch.com/index.php?page=article&article_id=20062 Leila Ghahramani Leila Ghahramani Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Seyed Vahid Hosseini Seyed Vahid Hosseini Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Ahmad Izadpanah Ahmad Izadpanah Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Alimohammad Bananzadeh Alimohammad Bananzadeh Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Mohammad Rezazadeh Kermani Mohammad Rezazadeh Kermani Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Alireza Safarpour Alireza Safarpour Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Mohsen Pirmoradi Mohsen Pirmoradi Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran; Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran. Tel: +98-9174859546 Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran; Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran. Tel: +98-9174859546
en 10.17795/acr-22329 Effective Attributes in Colorectal Cancer Relapse Using Artificial Neural Network and Cox Proportional Hazards Regression Effective Attributes in Colorectal Cancer Relapse Using Artificial Neural Network and Cox Proportional Hazards Regression research-article research-article Conclusions

The results showed superiority of the ANN method over the Cox PH model with respect to the area under the ROC and the accuracy rate in prediction. However, this method requires a large data set to learn the relations and cannot distinguish the confounding attributes.

Patients and Methods

A total of 184 patients with locoregional colorectal cancer, referred to Shahid Faghihi Hospital (Shiraz, Iran) for surgery, were followed in a five-year period for possible relapse during 2003-2011. Disease-free survival was then modeled based on the patients’ attributes, using Cox PH regression and ANN methods. All the attributes effective on disease relapse were investigated by these two methods.

Results

A total of 114 (62%) males and 70 (38%) females with a median age of 54 (range: 23-84) years old participated in the study. Among them, there were 95 (51.6%) patients with colon cancer and 89 (48.4%) with rectum cancer. In addition, 53 patients relapsed and 131 patients did not present any relapse or missed the follow up (censored data). The results showed that the accuracy rate in prediction was higher for the ANN method than the Cox PH model (78.2% versus 72.7%). In addition, the area under the receiver operating curve (ROC) was also more for the ANN method (0.86 versus 0.74). Five attributes of the patients, including neoadjuvant treatment, perforation and/or obstruction, perineural invasion, stage, and tumor grade, were significant through the Cox HP model. The first five attributes by the ANN method were surgeon, primary tumor site, perforation and/or obstruction, age, and adjuvant treatments. In this study, the order of attributes determined by the ANN method was rather confirmed by the physicians.

Background

The use of statistical methods to analyze data, regardless of their theoretical assumptions, leads to misinterpretation of the results.

Objectives

Effective attributes in colorectal cancer relapse were investigated through survival analysis in the present study. Comparison between the results of artificial neural network (ANN) method and Cox proportional hazards (Cox PH) model was the main purpose of this research.

Conclusions

The results showed superiority of the ANN method over the Cox PH model with respect to the area under the ROC and the accuracy rate in prediction. However, this method requires a large data set to learn the relations and cannot distinguish the confounding attributes.

Patients and Methods

A total of 184 patients with locoregional colorectal cancer, referred to Shahid Faghihi Hospital (Shiraz, Iran) for surgery, were followed in a five-year period for possible relapse during 2003-2011. Disease-free survival was then modeled based on the patients’ attributes, using Cox PH regression and ANN methods. All the attributes effective on disease relapse were investigated by these two methods.

Results

A total of 114 (62%) males and 70 (38%) females with a median age of 54 (range: 23-84) years old participated in the study. Among them, there were 95 (51.6%) patients with colon cancer and 89 (48.4%) with rectum cancer. In addition, 53 patients relapsed and 131 patients did not present any relapse or missed the follow up (censored data). The results showed that the accuracy rate in prediction was higher for the ANN method than the Cox PH model (78.2% versus 72.7%). In addition, the area under the receiver operating curve (ROC) was also more for the ANN method (0.86 versus 0.74). Five attributes of the patients, including neoadjuvant treatment, perforation and/or obstruction, perineural invasion, stage, and tumor grade, were significant through the Cox HP model. The first five attributes by the ANN method were surgeon, primary tumor site, perforation and/or obstruction, age, and adjuvant treatments. In this study, the order of attributes determined by the ANN method was rather confirmed by the physicians.

Background

The use of statistical methods to analyze data, regardless of their theoretical assumptions, leads to misinterpretation of the results.

Objectives

Effective attributes in colorectal cancer relapse were investigated through survival analysis in the present study. Comparison between the results of artificial neural network (ANN) method and Cox proportional hazards (Cox PH) model was the main purpose of this research.

Colorectal Cancer;Artificial Neural Network Method;Cox Proportional Hazards Model;Relapse Colorectal Cancer;Artificial Neural Network Method;Cox Proportional Hazards Model;Relapse http://www.colorectalresearch.com/index.php?page=article&article_id=22329 Saeedeh Pourahmad Saeedeh Pourahmad Colorectal Research Center, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran; Department of Biostatistics, Medical School, Shiraz University of Medical Sciences, Shiraz, IR Iran Colorectal Research Center, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran; Department of Biostatistics, Medical School, Shiraz University of Medical Sciences, Shiraz, IR Iran Bahareh Khosravi Bahareh Khosravi Department of Biostatistics, Medical School, Shiraz University of Medical Sciences, Shiraz, IR Iran Department of Biostatistics, Medical School, Shiraz University of Medical Sciences, Shiraz, IR Iran Mohammad Mohamadianpanah Mohammad Mohamadianpanah Colorectal Research Center, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran; Colorectal Research Center, Faghihi Hospital, Shiraz University of Medical Sciences, P. O. Box: 71936, Shiraz, IR Iran. Tel: +98-7116125168, Fax: +987116474320 Colorectal Research Center, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran; Colorectal Research Center, Faghihi Hospital, Shiraz University of Medical Sciences, P. O. Box: 71936, Shiraz, IR Iran. Tel: +98-7116125168, Fax: +987116474320
en 10.17795/acr-20233 Omental Mass Caused by Pericolic Vegetable Granuloma: A Rare Case Report Omental Mass Caused by Pericolic Vegetable Granuloma: A Rare Case Report case-report case-report Introduction

Foreign materials typically produce a reaction by multinucleated giant cells. Foreign bodies (such as vegetable cells in food material) in the omentum have not been reported to produce an omental mass. Vegetable cells surrounded by foreign body giant cells called vegetable granuloma/pulse granuloma by the previous literature are a peculiar type of granuloma caused by vegetable plant cells.

Case Presentation

Here in we present our experience with an old age lady who was operated with the impression of gastric mass. During the surgery no gastric mass was found but several omental masses were detected. Pathological study of the resected masses showed only vegetable cells in the omentum surrounded by an extensive foreign body giant cell granulomatous reaction, some of which were hyalinized. To the best of our knowledge such situation has not been reported in the English literature thus far.

Conclusions

In a patient with several omental granuloma, both in surgery and pathological examination, foreign body granuloma should be considered as a possible differential diagnosis.

Introduction

Foreign materials typically produce a reaction by multinucleated giant cells. Foreign bodies (such as vegetable cells in food material) in the omentum have not been reported to produce an omental mass. Vegetable cells surrounded by foreign body giant cells called vegetable granuloma/pulse granuloma by the previous literature are a peculiar type of granuloma caused by vegetable plant cells.

Case Presentation

Here in we present our experience with an old age lady who was operated with the impression of gastric mass. During the surgery no gastric mass was found but several omental masses were detected. Pathological study of the resected masses showed only vegetable cells in the omentum surrounded by an extensive foreign body giant cell granulomatous reaction, some of which were hyalinized. To the best of our knowledge such situation has not been reported in the English literature thus far.

Conclusions

In a patient with several omental granuloma, both in surgery and pathological examination, foreign body granuloma should be considered as a possible differential diagnosis.

Vegetable Granuloma;Omental Mass;Colon Vegetable Granuloma;Omental Mass;Colon http://www.colorectalresearch.com/index.php?page=article&article_id=20233 Bita Geramizadeh Bita Geramizadeh Department of Pathology, Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran; Department of Pathology, Transplant Research Center, Shiraz University of Medical Sciences, P. O. Box: 71345-1864, Shiraz, IR Iran. Tel/Fax: +98-7116474331 Department of Pathology, Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran; Department of Pathology, Transplant Research Center, Shiraz University of Medical Sciences, P. O. Box: 71345-1864, Shiraz, IR Iran. Tel/Fax: +98-7116474331 Seyed Javad Mousavi Seyed Javad Mousavi Department of Pathology, Shiraz University of Medical Sciences, Shiraz, IR Iran Department of Pathology, Shiraz University of Medical Sciences, Shiraz, IR Iran Alimohammad Bananzadeh Alimohammad Bananzadeh Department of Surgery, Colorectal and laparoscopy Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Department of Surgery, Colorectal and laparoscopy Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
en 10.17795/acr-17983 Colorectal Injuries in Minimal Invasive Urologic Surgery Colorectal Injuries in Minimal Invasive Urologic Surgery letter letter Urologic Surgical Procedures;Colorectal Surgery;Complications Urologic Surgical Procedures;Colorectal Surgery;Complications http://www.colorectalresearch.com/index.php?page=article&article_id=17983 Mohammad Mehdi Hosseini Mohammad Mehdi Hosseini Nephrology-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Nephrology-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Alireza Aminsharifi Alireza Aminsharifi Alireza Aminsharifi, Endourology Unit, Department of Urology, Shiraz University of Medical Sciences, Shiraz, IR Iran. Tel: +98-7112331006, Fax: +98-7112330724 ; Endourology Unit, Department of Urology, Shiraz University of Medical Sciences, Shiraz, IR Iran Alireza Aminsharifi, Endourology Unit, Department of Urology, Shiraz University of Medical Sciences, Shiraz, IR Iran. Tel: +98-7112331006, Fax: +98-7112330724 ; Endourology Unit, Department of Urology, Shiraz University of Medical Sciences, Shiraz, IR Iran Mohsen Rastegari Mohsen Rastegari Nephrology-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Nephrology-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Ali Eslahi Ali Eslahi Nephrology-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Nephrology-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Shahrokh Jahanbini Shahrokh Jahanbini Nephrology-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran Nephrology-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
en 10.17795/acr-21508 Why Hem-o-lok is Superior to the Other Methods of Securing the Base of Appendix in Complicated Appendicitis of Children? Why Hem-o-lok is Superior to the Other Methods of Securing the Base of Appendix in Complicated Appendicitis of Children? letter letter Appendix;End Loop;Stapler;Titanium;Clip Appendix;End Loop;Stapler;Titanium;Clip http://www.colorectalresearch.com/index.php?page=article&article_id=21508 Samir Delibegovic Samir Delibegovic Department of Surgery, Faculty of Medicine, University Clinical Center, University of Tuzla, Tuzla, Bosnia and Herzegovina; Department of Surgery, Faculty of Medicine, University Clinical Center, University of Tuzla, Tuzla, Bosnia and Herzegovina. Tel: +387-35303279, Fax: +387-35250474 Department of Surgery, Faculty of Medicine, University Clinical Center, University of Tuzla, Tuzla, Bosnia and Herzegovina; Department of Surgery, Faculty of Medicine, University Clinical Center, University of Tuzla, Tuzla, Bosnia and Herzegovina. Tel: +387-35303279, Fax: +387-35250474
en 10.17795/acr-21368 Laparoscopic Appendectomy in Complicated Appendicitis of Children Laparoscopic Appendectomy in Complicated Appendicitis of Children letter letter Complications;Appendicitis;Laparoscopy Complications;Appendicitis;Laparoscopy http://www.colorectalresearch.com/index.php?page=article&article_id=21368 Abdulzahra Hussain Abdulzahra Hussain Princess Royal University Hospital, Orpington, UK; Princess Royal University Hospital, Orpington, BR6 8ND, UK. Tel: +44-1689864905, Fax: +44-1689864488 Princess Royal University Hospital, Orpington, UK; Princess Royal University Hospital, Orpington, BR6 8ND, UK. Tel: +44-1689864905, Fax: +44-1689864488
en 10.17795/acr-17847 Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman letter letter Congenital Arteriovenous Malformations;Colonoscopy;Rectal Bleeding;Colitis, Ulcerative Congenital Arteriovenous Malformations;Colonoscopy;Rectal Bleeding;Colitis, Ulcerative http://www.colorectalresearch.com/index.php?page=article&article_id=17847 Saeed Derakhshani Saeed Derakhshani Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran; Parsian Hospital, Tehran, IR Iran Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran; Parsian Hospital, Tehran, IR Iran Mehran Babaei Mehran Babaei Parsian Hospital, Tehran, IR Iran Parsian Hospital, Tehran, IR Iran Mojgan Forootan Mojgan Forootan Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Nakisa Maghsoodi Nakisa Maghsoodi Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Seyed Ali Majdzadeh Seyed Ali Majdzadeh Parsian Hospital, Tehran, IR Iran; Parsian Hospital, Tehran, IR Iran. Tel: +98-9359356667, Fax: +98-2122938262 Parsian Hospital, Tehran, IR Iran; Parsian Hospital, Tehran, IR Iran. Tel: +98-9359356667, Fax: +98-2122938262