Annals of Colorectal Research

Published by: Kowsar

A Diagnostic Conundrum in a Newly Diagnosed Ulcerative Colitis Patient Who Presented with Pleuropericardial Effusion

Alpaslan Tanoglu 1 , * , Omer Tekin 2 , Tolga Duzenli 1 , Muammer Kara 1 , Mustafa Kaplan 1 , Irfan Kucuk 1 , Onur Ozari 1 and Yusuf Yazgan 1
Authors Information
1 Department of Gastroenterology, Sultan Abdulhamid Han Training and Research Hospital, Health Sciences University, Istanbul, Turkey
2 Department of Internal Medicine, Sultan Abdulhamid Han Training and Research Hospital, Health Sciences University, Istanbul, Turkey
Article information
  • Annals of Colorectal Research: 7 (2); e84743
  • Published Online: July 6, 2019
  • Article Type: Case Report
  • Received: September 29, 2018
  • Revised: April 7, 2019
  • Accepted: April 15, 2019
  • DOI: 10.5812/acr.84743

How to Cite: Tanoglu A, Tekin O, Duzenli T, Kara M, Kaplan M, et al. A Diagnostic Conundrum in a Newly Diagnosed Ulcerative Colitis Patient Who Presented with Pleuropericardial Effusion, Ann Colorectal Res. Online ahead of Print ; 7(2):e84743. doi: 10.5812/acr.84743.

Copyright © 2019, Annals of Colorectal Research. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Discussion
  • 1. Gisbert JP, Chaparro M. Acute severe ulcerative colitis: State of the art treatment. Best Pract Res Clin Gastroenterol. 2018;32-33:59-69. doi: 10.1016/j.bpg.2018.05.007. [PubMed: 30060940].
  • 2. Beyazit Y, Sayilir A, Tanoglu A, Kekilli M, Kocak E, Ekiz F, et al. Plasma thrombin-activatable fibrinolysis inhibitor levels correlate with the disease activity of ulcerative colitis. Intern Med. 2016;55(14):1831-6. doi: 10.2169/internalmedicine.55.6473. [PubMed: 27432089].
  • 3. Kekilli M, Tanoglu A. Inflammatory bowel disease is frequently encountered in Turkey and Iran but Less than North and West Europe. Ann Colorectal Res. 2013;1(3):111. doi: 10.17795/acr-14460.
  • 4. Abu-Hijleh M, Evans S, Aswad B. Pleuropericarditis in a patient with inflammatory bowel disease: A case presentation and review of the literature. Lung. 2010;188(6):505–10. doi: 10.1007/s00408-010-9259-y.
  • 5. Tozzi A, Biagini MR, Rastelli C, Galli A, Baldi D, Milani S. Mesalamine-induced pleuritis in a patient with ulcerative colitis. Inflamm Bowel Dis. 2009;15(1):158-9. doi: 10.1002/ibd.20533. [PubMed: 18629902].
  • 6. Storch I, Sachar D, Katz S. Pulmonary manifestations of inflammatory bowel disease. Inflamm Bowel Dis. 2003;9(2):104-15. doi: 10.1097/00054725-200303000-00004. [PubMed: 12769444].
  • 7. Moles KW, Varghese G, Hayes JR. Pulmonary involvement in ulcerative colitis. Br J Dis Chest. 1988;82:79-83. doi: 10.1016/0007-0971(88)90012-5.
  • 8. Patwardhan RV, Heilpern RJ, Brewster AC, Darrah JJ. Pleuropericarditis: An extraintestinal complication of inflammatory bowel disease. Report of three cases and review of literature. Arch Intern Med. 1983;143(1):94-6. [PubMed: 6849612].
  • 9. Basseri B, Enayati P, Marchevsky A, Papadakis KA. Pulmonary manifestations of inflammatory bowel disease: Case presentations and review. J Crohns Colitis. 2010;4(4):390-7. doi: 10.1016/j.crohns.2010.03.008. [PubMed: 21122534].
  • 10. Oxentenko AS, Loftus EV, Oh JK, Danielson GK, Mangan TF. Constrictive pericarditis in chronic ulcerative colitis. J Clin Gastroenterol. 2002;34(3):247-51. [PubMed: 11873106].
  • 11. Foster RA, Zander DS, Mergo PJ, Valentine JF. Mesalamine-related lung disease: Clinical, radiographic, and pathologic manifestations. Inflamm Bowel Dis. 2003;9(5):308-15. doi: 10.1097/00054725-200309000-00004. [PubMed: 14555914].
  • 12. Morelock SY, Sahn SA. Drugs and the pleura. Chest. 1999;116(1):212-21. doi: 10.1378/chest.116.1.212. [PubMed: 10424528].
  • 13. Qanneta R, Garcia Pardo G, Florit Serra L. Acute pleuropericarditis in a patient with primary Sjogren's syndrome and quiescent ulcerative colitis in longstanding 5-aminosalicylic acid therapy. J Crohns Colitis. 2013;7(10):e506-7. doi: 10.1016/j.crohns.2013.05.008. [PubMed: 23768863].
  • 14. Calafat M, Manosa M, Cabre E, Domenech E. [Acute pericarditis associated with oral or topical mesalazine therapy in patients with ulcerative colitis]. Gastroenterol Hepatol. 2014;37(4):254-5. Spanish. doi: 10.1016/j.gastrohep.2013.09.004. [PubMed: 24333139].
  • 15. Ji XQ, Wang LX, Lu DG. Pulmonary manifestations of inflammatory bowel disease. World J Gastroenterol. 2014;20(37):13501-11. doi: 10.3748/wjg.v20.i37.13501. [PubMed: 25309080]. [PubMed Central: PMC4188901].
  • 16. Desai D, Patil S, Udwadia Z, Maheshwari S, Abraham P, Joshi A. Pulmonary manifestations in inflammatory bowel disease: A prospective study. Indian J Gastroenterol. 2011;30(5):225-8. doi: 10.1007/s12664-011-0129-1. [PubMed: 21935713].
  • 17. Bunu DM, Timofte CE, Ciocoiu M, Floria M, Tarniceriu CC, Barboi OB, et al. Cardiovascular manifestations of inflammatory bowel disease: Pathogenesis, diagnosis, and preventive strategies. Gastroenterol Res Pract. 2019;2019:3012509. doi: 10.1155/2019/3012509. [PubMed: 30733802]. [PubMed Central: PMC6348818].
  • 18. Mitchell NE, Harrison N, Junga Z, Singla M. Heart under attack: Cardiac manifestations of inflammatory bowel disease. Inflamm Bowel Dis. 2018;24(11):2322-6. doi: 10.1093/ibd/izy157. [PubMed: 29788235].
  • 19. Park EH, Kim BJ, Huh JK, Jeong EH, Lee SH, Bang KB, et al. Recurrent mesalazine-induced myopericarditis in a patient with ulcerative colitis. J Cardiovasc Ultrasound. 2012;20(3):154-6. doi: 10.4250/jcu.2012.20.3.154. [PubMed: 23185660]. [PubMed Central: PMC3498314].
  • 20. Blum A, Shalabi R, Brofman T, Shajrawi I. Cardiac manifestations of ulcerative colitis. Isr Med Assoc J. 2009;11(12):764-5.
  • 21. Rothfuss KS, Stange EF, Herrlinger KR. Extraintestinal manifestations and complications in inflammatory bowel diseases. World J Gastroenterol. 2006;12(30):4819-31. doi: 10.3748/wjg.v12.i30.4819. [PubMed: 16937463]. [PubMed Central: PMC4087615].

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