Annals of Colorectal Research

Letter

1/6/2015

Combined Technique in the Management of Complex Pilonidal Disease

Seyed Vahid Hosseini, Alimohamamad Bananzadeh

Brief Report

1/6/2015

Frequency of Different Psychiatric Disorders in Patients With Functional Bowel Disorders: A Short Report

Bahareh Fakhraei, Ali Firouzabadi, Mojtaba Farjam, Mohammad Reza Fattahi, Mohamad Hasan Kazemi, Mahvash Alizade Naini, Maryam Moini

Letter

1/6/2015

Is Clinical Evaluation Sufficient for Decision Making in Patients With Penetrating Abdominal Trauma?

Ahmad Izadpanah

Research Article

1/6/2015

Comparison of Oncologic Short Term Results of Laparoscopic Versus Open Surgery of Rectal Cancer

Ehsan Solati, Ghodratollah Maddah, Abbas Abdollahi, Alireza Tavassoli, Masoumeh Safaei, Mehdi Jabbari Nooghabi

Patients and Methods: This descriptive-analytic study was performed on 88 patients with middle and lower rectal cancer in the two equivalent groups of laparoscopic and open surgery in Mashhad Ghaem and Omid hospitals during 2011 - 2013. Information including age, sex, number of removed and involved lymph nodes, proximal, distal, and radial margins, tumor stage and location, recurrence and disease-free survival collected in the questionnaire and analyzed using descriptive statistics and frequency distribution tables and t-test.

Results: Both groups of open and laparoscopic surgery had similar characteristics of age, sex, recurrence and disease-free survival, tumor margins and one-year mortality. The number of removed and involved lymph nodes was higher in the laparoscopic group (5.16 vs. 3.55, respectively, with P < 0.050, and 1.74 vs. 0.59 with P = 0.023), but the ratio of involved lymph nodes to the total number of removed lymph nodes was not different between the two groups (LNR) (P = 0.071). Tumor stage was higher in the laparoscopic group and most were in stages II and III (P < 0.001).

Review Article

1/6/2015

Laparoscopy and Intra-Abdominal Sepsis

Peter Edward Coyne, Reza Kalbassi

Context: Intra-abdominal sepsis has significant morbidity and mortality. In the developed world, there are many common causes originating from the lower gastrointestinal tract including diverticular disease, appendicitis, perforated cancers, and inflammatory bowel disease. It has a high cost and is associated with high levels of significant morbidity and mortality. Management options include radiologic drainage and surgical options include resection for more widespread sepsis. Laparoscopic surgery has increased and has been useful in elective setting. Its use in the emergency setting is less evaluated.

Results: Laparoscopic surgery has been shown to have a role in the acute setting. Studies show it has become the gold standard in the appendicitis. High quality Randomized controlled trials are in short supply but observational and cohort studies have shown equivalence and with increasing experience complication rates are reduced. Evidence is also increasing in the management of diverticular disease, crohn’s and ulcerative colitis as well as post-operative complication management and acute presentations of colorectal cancer.

Case Report

1/6/2015

Extramedullary Hematopoiesis in a Man With β-Thalassemia: An Uncommon Cause of an Adrenal Mass

Shahryar Zeighami, Seyed Ali Eslahi, Mohammad Mehdi Hosseini, Ali Ariafar, Sara Pakbaz, Mohsen Rastegari, Hajar Khazraei

Research Article

1/6/2015

Antioxidant and Anti-Inflammatory Effects of Gel and Aqueous Extract of Melilotus officinalis L. in Induced Ulcerative Colitis: A Rattus norvegicus Model

Ali Reza Safarpour, Fatemeh Kaviyani, Masood Sepehrimanesh, Nasrollah Ahmadi, Omid Koohi Hosseinabadi, Nader Tanideh, Najmeh Showraki

Materials and Methods: The plant aqueous extraction and high performance liquid chromatography and Ferric Reducing Antioxidant Power (FRAP) assay were performed on aqueous extract to identify its compounds and antioxidant activities. Also, 70 adult male rats were and UC was induced using 3% acetic acid solution. They received different daily doses of M. officinalis L. in two forms (orally, 500 and 1000 mg/kg) and gel extract (10% and 20%). On the 7th day, the colon tissues were examined regarding the macroscopic and histopathology lesions plus oxidative stress and compared to the positive and negative control groups.

Results: HPLC analysis revealed that five grams of the flower powder contained 9.7 mg gallic acid, 99 mg catechin, 21.9 mg caffeic acid, 0.86 mg chlorogenic acid, 1.13 mg quercetin, 548.9 mg cinnamic acid, 289 mg coumarin and 126 mg p-coumaric acid. The FRAP value of the extract was 2.91 ± 0.14 μM/g. There were significant differences between the group of rats which received the gel or aqueous extract of the flower compared to the negative control group using normal saline and the base gel and they had no significant differences with the positive control group using the Asacol, regarding the pathologic, malondialdehyde, and weight improvements.

Annals of Colorectal Research: Jun 2015, 3 (2), 7 articles.